More concerns for e-cigarettes

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Flavoring Chemicals In E-Cigarettes May Harm Airway Passages, Study Suggests.

Reuters (2/22, Mishra) reported a small test tube experiment examining the effect of e-cigarette flavoring chemicals on bronchial epithelial cells found the “chemicals induced hundreds of genetic changes in the cells” and “impaired the ability of the cells to function properly.” The chemicals studied were diacetyl and 2,3-pentanedione. Study co-author Joseph Allen, from the Harvard T.H. Chan School of Public Health, explained that while “these flavoring chemicals are what we call Generally Regarded As Safe (GRAS)” for the ingestion pathway, “they have not been tested for inhalation safety.” Moreover, he said, “These flavoring chemicals…can cause severe lung disease” when inhaled. Allen added that “some of the newer e-cigarette companies like Juul are starting to advertise that their products do not contain (these chemicals).” The study was published in Scientific Reports.

For information on the ADA’s advocacy efforts on tobacco, visit

The ADA has resources to assist dentists in talking with their patients about tobacco cessation, including an online continuing education course, Tobacco Policy, Pharmacotherapy, and Dentistry; an ADA Science Institute-developed Oral Health Topics webpage on smoking and tobacco cessation; and the brochures “Tobacco and Oral Health” and “Get the Facts About Mouth and Throat Cancer.”

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